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Research on Immune Response to PCV in Preterm Infants Earns ESPID-PIDJ Award

Created May 29 2018, 04:21 PM by Wolters Kluwer Health
  • The Pediatric Infectious Disease Journal

May 29, 2018 – A study showing that pneumococcal vaccination produces a lasting antibody response in preterm infants has been named winner of the inaugural ESPID-PIDJ Award, recognizing the best paper submitted to The Pediatric Infectious Disease Journal (PIDJ) by a member of The European Society for Paediatric Infectious Diseases (ESPID). The Pediatric Infectious Disease Journal, the official journal of the ESPID, is published in the Lippincott portfolio by Wolters Kluwer.

The lead author of the winning paper is Federico Martinón-Torres, MD, PhD, of Healthcare Research Institute of Santiago, Santiago de Compostela, Spain. Dr. Martinón-Torres will receive the ESPID-PIDJ Award and briefly discuss his work at a ceremony during the 36th Annual Meeting of the ESPID (ESPID 2018), held this week in Malmö, Sweden.

Winning Paper Shows Persistent Response to PCV-13 in Preterm Infants

Dr. Martinón-Torres and colleagues evaluated the persistence of antibody response to the recommended four-dose course of 13-valent PCV vaccine in formerly preterm infants, compared to term infants. The researchers found that immune responses persisted up to two years after the "toddler dose" (scheduled for age 12 months) of PCV13.

For most serotypes, IgG-binding antibody levels were lower for preterm infants, compared to term infants, at both one and two years after the toddler dose. However, antibody levels in the two groups of children appeared "functionally comparable."

The findings have important implications for reducing the elevated risk of invasive pneumococcal disease in preterm infants. Dr. Martinón-Torres and coauthors conclude, "The routine (3 + 1) vaccination schedule is likely to offer long-term protection against invasive pneumococcal disease in preterm infants and should be initiated regardless of gestational age or weight at birth, without delay of the toddler dose."

Steven Black, MD, Editor-in-Chief of PIDJ, comments: "These findings underscore the importance of current PCV recommendations for maximizing protection against invasive pneumococcal disease in preterm infants at high risk."

Presented this year for the first time, the new ESPID-PIDJ Award recognizes the best original research paper submitted to PIDJ by an ESPID member during the preceding year, as determined by the ESPID Awards Committee. Prof. Adam Finn, President of ESPID, comments, "The goal of this new award is to highlight the partnership between ESPID and PIDJ, and to recognize the excellence of the scientific work being performed by ESPID members."

Dr. Black adds, "When it's time to publish their research, we encourage all ESPID members to consider submitting to PIDJ, their subspecialty society journal." To learn about submitting your manuscript, visit http://www.editorialmanager.com/pidj/default.aspx.

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About The Pediatric Infectious Disease Journal

The Pediatric Infectious Disease Journal® (PIDJ) is a complete, up-to-the-minute resource on infectious diseases in children. Through a mix of original studies, informative review articles, and unique case reports, PIDJ delivers the latest insights on combating disease in children — from state-of-the-art diagnostic techniques to the most effective drug therapies and other treatment protocols. It is a resource that can improve patient care and stimulate your personal research. The Pediatric Infectious Disease Journal is the official journal of the European Society for Paediatric Infectious Diseases.

About The European Society for Paediatric Infectious Diseases

Now in its 36th year, The European Society for Paediatric Infectious Diseases (ESPID) forms the basis for European investigators interested in infectious diseases in children and infection prevention in childhood. The society is engaged in a number of activities including the organisation of multicentre trials, international exchange of infectious disease fellows, and an annual meeting. Membership includes subscription to The Pediatric Infectious Disease Journal® in addition to many other benefits.

About Wolters Kluwer

Wolters Kluwer is a global leader in professional information, software solutions, and services for the health, tax & accounting, finance, risk & compliance, and legal sectors. We help our customers make critical decisions every day by providing expert solutions that combine deep domain knowledge with specialized technology and services.

Wolters Kluwer, headquartered in the Netherlands, reported 2017 annual revenues of €4.4 billion. The company serves customers in over 180 countries, maintains operations in over 40 countries, and employs approximately 19,000 people worldwide.

Wolters Kluwer Health is a leading global provider of trusted clinical technology and evidence-based solutions that engage clinicians, patients, researchers and students with advanced clinical decision support, learning and research and clinical intelligence. For more information about our solutions, visit http://healthclarity.wolterskluwer.com and follow us on LinkedIn and Twitter @WKHealth.

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